Lima José L F C, Santos João L M, Dias Ana C B, Ribeiro Marta F T, Zagatto Elias A G
REQUIMTE, Departamento de Quimica-Fisica, Faculdade de Farmácia, Universidade do Porto, Rua Anibal Cunha 164, Porto 4050, Portugal.
Talanta. 2004 Dec 15;64(5):1091-8. doi: 10.1016/j.talanta.2004.04.034.
Multi-pumping flow systems (MPFS) are one of the most recent developments in terms of the design, conception and implementation of continuous flow methodologies, for sample and reagent handling and for the automation of analytical procedures. Based on the utilisation of multiple solenoid micro-pumps they enable the configuring of fully automated and easily controlled and operated analytical systems since all the fundamental operations involved in carrying out a sample analysis, including sample insertion, reagent addition and signal measurement could be carried out by the same manifold component, reducing the number of system parts and minimising its control or the occurrence of mal-functions. On the other hand, micro-pumps actuation produce a pulsed flow characterised by a chaotic movement of the solutions, which contributes to a fast sample/reagent homogenisation with low axial dispersion yielding improved analytical signals. The combination of such advantageous features resulted in simple, compact, versatile, fast, low-cost analytical procedures, exhibiting low reagent and low sample consumption, reducing the production of undesirable wastes and minimising operator intervention.
