Olieman Joanne F, Tibboel Dick, Penning Corine
Department of Pediatric Surgery, Erasmus MC-Sophia Children's Hospital, The Netherlands.
J Pediatr Surg. 2008 Nov;43(11):2061-9. doi: 10.1016/j.jpedsurg.2008.04.017.
The aim of this retrospective study is to describe characteristics of the first year of infantile short bowel syndrome (SBS), with regard to nutritional correlates and growth. Differences in outcome between decade 1980 (1980 to 1990) and decade 1990 (1990 to 2000) were studied.
Children with infantile SBS, who had been admitted in their first year of life between January 1975 and January 2002, were included. Patient characteristics, duration of parenteral nutrition (PN), type of enteral nutrition, and every quarterly term weight and height for age were collected. Data of decade 1980 and decade 1990 were compared, using appropriate statistical analysis.
Twenty-eight patients were identified for decade 1980 vs 62 patients in decade 1990. Length of stay was significantly shorter in decade 1990 (116 vs 182 days; P = .018). Residual bowel length was not significantly longer in the latter decade (74 cm vs 60 cm; not significant [ns]). Mean weight for age (SD score [SDS]) in the first year of SBS in decade 1980 was significantly lower than in decade 1990 (0.9 SDS; P = .035).
Improved care of patients with SBS and the slightly longer residual bowel length (ns) in decade 1990 resulted in shorter length of stay, shorter duration of PN, and significantly higher SDS for weight for age compared with decade 1980.
本回顾性研究旨在描述婴儿短肠综合征（SBS）第一年的特征，涉及营养相关性和生长情况。研究了1980年代（1980年至1990年）和1990年代（1990年至2000年）之间结局的差异。
纳入1975年1月至2002年1月间在出生第一年就入院的婴儿SBS患儿。收集患者特征、肠外营养（PN）持续时间、肠内营养类型以及每季度的年龄别体重和身高数据。使用适当的统计分析方法比较1980年代和1990年代的数据。
1980年代确定了28例患者，而1990年代有62例患者。1990年代的住院时间明显更短（116天对182天；P = 0.018）。后一个十年的残余肠长度并没有显著更长（74厘米对60厘米；无显著差异[ns]）。1980年代SBS第一年的年龄别平均体重（标准差评分[SDS]）显著低于1990年代（0.9 SDS；P = 0.035）。
与1980年代相比，1990年代对SBS患者护理的改善以及残余肠长度略长（无显著差异）导致住院时间缩短、PN持续时间缩短，且年龄别体重的SDS显著更高。
