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腹腔镜下子宫血管阻断术治疗有症状子宫肌瘤女性,加或不加腹腔镜下子宫肌瘤切除术:4年结果

Laparoscopic uterine vessel occlusion in the treatment of women with symptomatic uterine myomas with and without adding laparoscopic myomectomy: 4-year results.

作者信息

Wang Peng-Hui, Liu Wei-Min, Fuh Jong-Ling, Chao Hsiang-Tai, Chao Kuan-Chong, Yuan Chiou-Chong

机构信息

Department of Obstetrics and Gynecology, National Yang-Ming University School of Medicine and Taipei Veterans General Hospital, Taipei, Taiwan.

出版信息

J Minim Invasive Gynecol. 2008 Nov-Dec;15(6):712-8. doi: 10.1016/j.jmig.2008.08.005.

Abstract

STUDY OBJECTIVE

To estimate the necessity of laparoscopic myomectomy (LM) in the treatment of women with symptomatic uterine myomas who are undergoing laparoscopic uterine vessel occlusion (LUVO).

DESIGN

A comparative observational study (Canadian Task Force classification II-3).

SETTING

Medical center.

PATIENTS

In all, 163 patients with symptomatic, uncomplicated myomas warranting myomectomy. A total of 95 patients underwent LUVO and 68 underwent LUVO with LM.

INTERVENTIONS

Symptomatic myomas treated by LUVO with or without LM.

MEASUREMENTS AND MAIN RESULTS

The outcome was measured by comparing surgical parameters, immediate postoperative parameters, 4-year evaluations of symptom control, and reintervention (hysterectomy or myomectomy) in both groups. The general characteristics of the patients were similar in both groups. No statistical differences existed in complications, success rate, or immediate satisfaction rate between the 2 groups. Compared with LUVO+LM, LUVO had advantages in surgical and immediate postoperative parameters, including less operative time, minimal blood loss, and rapid postoperative recovery; however, LUVO+LM was superior to LUVO in terms of a better and longer duration of symptom relief, a higher level of satisfaction, and avoidance of reintervention. Of the sexually active patients who did not use contraception, 58.8% (10/17) and 66.7% (4/6) became pregnant in groups I and II, respectively (no statistical significance).

CONCLUSION

Although LUVO is a less invasive procedure in the treatment of most women with symptomatic myomas, it is also less effective for symptom control and has shorter durable symptom relief compared with LUVO+LM. Reoperation can be avoided in most patients who are treated with LUVO+LM.

摘要

研究目的

评估在对有症状的子宫肌瘤女性进行腹腔镜子宫血管阻断术(LUVO)时,行腹腔镜子宫肌瘤切除术(LM)的必要性。

设计

一项比较性观察研究(加拿大工作组分类II-3)。

地点

医疗中心。

患者

总共163例有症状、无并发症且需要行子宫肌瘤切除术的患者。其中95例行LUVO,68例行LUVO联合LM。

干预措施

有症状的子宫肌瘤采用LUVO治疗,可联合或不联合LM。

测量指标及主要结果

通过比较两组的手术参数、术后即刻参数、症状控制的4年评估结果以及再次干预情况(子宫切除术或子宫肌瘤切除术)来衡量结局。两组患者的一般特征相似。两组在并发症、成功率或即刻满意率方面无统计学差异。与LUVO联合LM相比,LUVO在手术及术后即刻参数方面具有优势,包括手术时间更短、出血量极少以及术后恢复快;然而,在症状缓解的程度和持续时间、满意度更高以及避免再次干预方面,LUVO联合LM优于LUVO。在未采取避孕措施的性活跃患者中,I组和II组的妊娠率分别为58.8%(10/17)和66.7%(4/6)(无统计学意义)。

结论

尽管LUVO在治疗大多数有症状的子宫肌瘤女性时侵入性较小,但与LUVO联合LM相比,其在症状控制方面效果较差,症状缓解的持续时间较短。大多数接受LUVO联合LM治疗的患者可避免再次手术。

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