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采用腹腔镜子宫血管阻断术及随后立即行子宫肌瘤切除术治疗有症状的子宫肌瘤:哪种是最佳手术方式?

Symptomatic myoma treated with laparoscopic uterine vessel occlusion and subsequent immediate myomectomy: which is the optimal surgical approach?

作者信息

Wang Peng-Hui, Liu Wei-Min, Fuh Jong-Ling, Chao Hsiang-Tai, Yuan Chiou-Chung, Chao Kuan-Chong

机构信息

Department of Obstetrics and Gynecology, National Yang-Ming University School of Medicine and Taipei Veterans General Hospital, Taipei, Taiwan.

出版信息

Fertil Steril. 2009 Aug;92(2):762-9. doi: 10.1016/j.fertnstert.2008.06.038. Epub 2008 Oct 18.

Abstract

OBJECTIVE

To determine the optimal surgical approach when patients are treated with laparoscopic uterine vessel occlusion (LUVO) combined with myomectomy in the management of women with symptomatic uterine fibroids.

DESIGN

An observational study.

SETTING

Medical centers.

PATIENT(S): One hundred thirty-one patients with symptomatic myomas underwent LUVO plus laparoscopic myomectomy (LM; LUVO+LM) (n = 49) or LUVO plus ultra-mini laparotomy UMLT-M (LUVO+UMLT-M) (n = 82).

INTERVENTION(S): Myomectomy through laparoscopy or UMLT access.

MAIN OUTCOME MEASURE(S): The outcome was measured by comparing surgical techniques, and 3-year follow-up, including symptom control and reintervention (hysterectomy or myomectomy), in both groups.

RESULT(S): General characteristics of the patients were similar in both groups, except the number of myomas. Surgical techniques seemed to be easier in the LUVO+UMLT-M group than in LUVO+LM group, because of less operation time (56.1 +/- 16.9 minutes vs. 73.4 +/- 26.9 minutes; P=.009) and a higher success rate (100% vs. 91.8%; P=.018). There were no differences in the 3-year follow-up of the therapeutic outcomes of the LUVO+UMLT-M and LUVO+LM groups, with low reintervention rates (1.2% vs. 0) and good symptom control rates in both groups.

CONCLUSION(S): The LUVO+LM, either through laparoscopy or UMLT, was acceptable in the management of symptomatic uterine fibroids. However, the LUVO+UMLT-M technique might be more feasible, as it required less operative time and had a higher success rate.

摘要

目的

确定在有症状子宫肌瘤女性的治疗中,腹腔镜子宫血管阻断术(LUVO)联合肌瘤切除术时的最佳手术方式。

设计

一项观察性研究。

地点

医疗中心。

患者

131例有症状肌瘤患者接受了LUVO联合腹腔镜肌瘤切除术(LM;LUVO+LM)(n = 49)或LUVO联合超小切口剖腹术(UMLT-M)(LUVO+UMLT-M)(n = 82)。

干预措施

通过腹腔镜或UMLT入路进行肌瘤切除术。

主要观察指标

通过比较两组的手术技术以及3年随访结果(包括症状控制和再次干预(子宫切除术或肌瘤切除术))来衡量结局。

结果

两组患者的一般特征相似,但肌瘤数量不同。LUVO+UMLT-M组的手术技术似乎比LUVO+LM组更容易,因为手术时间更短(56.1±16.9分钟对73.4±26.9分钟;P = 0.009)且成功率更高(100%对91.8%;P = 0.018)。LUVO+UMLT-M组和LUVO+LM组治疗结局的3年随访结果无差异,两组的再次干预率均较低(1.2%对0)且症状控制率良好。

结论

LUVO联合LM,无论是通过腹腔镜还是UMLT,在有症状子宫肌瘤的治疗中都是可以接受的。然而,LUVO+UMLT-M技术可能更可行,因为它所需手术时间更少且成功率更高。

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