Bron A, Baudouin C, Denis P, Nordmann J-P, Renard J-P, Rouland J-F, Sellem E
Service d'Ophtalmologie, CHU Hôpital Général, Dijon, France.
J Fr Ophtalmol. 2008 Sep;31(7):659-65. doi: 10.1016/s0181-5512(08)74379-1.
To evaluate satisfaction and compliance in glaucoma and ocular hypertensive patients receiving a fixed combination treatment.
After instilling a fixed combination, patients were asked to fill out a questionnaire about their satisfaction and compliance at baseline and 15 days after the onset of new therapy.
1693 glaucoma patients (G) and 621 ocular hypertensive (OHT) patients were included. Mean age was 65.6+/-11.7 years. Onset of disease was 7.2+/-6.6 years and 5.2+/-4.9 years for G and OHT patients, respectively. Insufficient efficacy of the previous topical treatment (monotherapy in 55% of cases) was the main cause for shifting to a fixed combination in 70% of cases. Satisfaction was increased in 15% of the patients and compliance was increased in 25% of the patients.
Fixed combination provides an easier regimen and therefore encourages better compliance, a key issue in a chronic disease such as glaucoma.
评估接受固定复方治疗的青光眼和高眼压症患者的满意度及依从性。
滴入固定复方药物后，要求患者在基线期及新治疗开始15天后填写一份关于其满意度和依从性的问卷。
纳入1693例青光眼患者（G组）和621例高眼压症患者（OHT组）。平均年龄为65.6±11.7岁。G组和OHT组患者的疾病发病时间分别为7.2±6.6年和5.2±4.9年。在70%的病例中，先前局部治疗效果不佳（55%的病例为单一疗法）是转而使用固定复方药物的主要原因。15%的患者满意度提高，25%的患者依从性提高。
固定复方提供了一种更简便的治疗方案，因此有助于提高依从性，这在青光眼等慢性疾病中是一个关键问题。
