Frydrychowicz Alex, Bley Thorsten A, Zadeh Zahra Abdullah, Harloff Andreas, Winterer Jan T, Hennig Jürgen, Langer Mathias, Markl Michael
Department of Diagnostic Radiology and Medical Physics, University Hospital Freiburg, Germany.
J Magn Reson Imaging. 2008 Nov;28(5):1116-24. doi: 10.1002/jmri.21554.
To qualitatively and quantitatively evaluate the image quality in accelerated time-resolved 3D contrast-enhanced MR angiography (tr-CE-MRA) at 3T.
In all, 113 MRA were performed in 107 patients on a 3T MR system after written informed consent and approval by the ethics committee. Twenty consecutive thoracic (n=87) or craniocervical (n=26) 3D data volumes were acquired. The timeframes with maximum arterial and venous contrast were determined and a total of 663 arterial and venous segments were analyzed by two blinded observers. Diagnostic image quality was graded by applying a 0 (low) to 3 (excellent) scale. Additionally, local signal-to-noise (SNR) and contrast-to-noise ratios (relative CNR) were evaluated.
Tr-CE-MRA was successfully performed in all patients. Good to excellent image quality (2.42+/-0.31) was observed in all individuals with preserved discrimination of arteries (2.43+/-0.48) and veins (2.20+/-0.56). Minor image degradation due to artifacts (2.62+/-0.25) and constantly high vascular signal and contrast were detected. There was a significant superiority of coronal orientation during thoracic MRA (P<0.05). In 18 cases tr-CE-MRA provided additional information on vascular pathologies.
Large field of view tr-CE-MRA enables constantly high-quality thoracic and craniocervical angiographies. In addition, the dynamics of tr-CE-MRA can offer additional information on vascular pathologies.
定性和定量评估3T场强下加速时间分辨三维对比增强磁共振血管造影（tr-CE-MRA）的图像质量。
在获得书面知情同意并经伦理委员会批准后，对107例患者在3T磁共振系统上共进行了113次MRA检查。连续采集20个胸部（n = 87）或颅颈（n = 26）的三维数据容积。确定动脉和静脉对比最强的时间帧，由两名不知情的观察者对总共663个动脉和静脉节段进行分析。采用0（差）至3（优）的评分标准对诊断图像质量进行分级。此外，还评估了局部信噪比（SNR）和对比噪声比（相对CNR）。
所有患者均成功完成tr-CE-MRA检查。所有个体的图像质量均为良好至优秀（2.42±0.31），动脉（2.43±0.48）和静脉（2.20±0.56）分辨清晰。检测到因伪影导致的轻微图像质量下降（2.62±0.25），血管信号和对比始终较高。胸部MRA检查中，冠状位方向具有显著优势（P<0.05）。在18例患者中，tr-CE-MRA提供了有关血管病变的额外信息。
大视野tr-CE-MRA能够持续提供高质量的胸部和颅颈血管造影图像。此外，tr-CE-MRA的动态成像可为血管病变提供额外信息。
