Zarudin V V, Gulianskiĭ L N, Fedosov E A, Gordilovskaia A P
Arkh Patol. 1976;38(11):33-9.
The article presents results of morphological, morphometric and cytochemical investigations of 100 placentae obtained in women who suffered from nephropathy of various degrees, and of placentae of mice with induced "graft versus host" reaction during pregnancy, and also of organs of two fetuses born to mothers who suffered from nephropathy of the III degree. In severe forms of late toxemia placentae, regularly showed infiltration of its structural elements with cells of the type of microlymphocytes with lytic properties. These changes occurred against the background of the placental metabolism turning into anaerobic respiration and they revealed a considerable degree of similarity to the changes in placentae of mice following the induction of the reaction "graft versus host". The morphological picture in lymphoid and other organs of the two investigated fetuses resembled very much that in "runt" disease.
本文呈现了对100例不同程度肾病女性所获胎盘、孕期发生诱导性“移植物抗宿主”反应的小鼠胎盘以及III度肾病母亲所生两名胎儿器官进行的形态学、形态计量学和细胞化学研究结果。在重度晚期毒血症胎盘病例中，其结构成分经常出现具有溶解特性的微淋巴细胞类型细胞浸润。这些变化发生在胎盘代谢转变为无氧呼吸的背景下，并且与诱导“移植物抗宿主”反应后小鼠胎盘的变化表现出相当程度的相似性。两名被研究胎儿的淋巴及其他器官的形态学表现与“发育不全”病极为相似。
