Szarvas Z, Treit P
Morphol Igazsagugyi Orv Sz. 1977 Apr;17(2):99-107.
Ultrastructural changes of the placenta in toxemia of pregnancy and in diabetes are described. In toxemia of pregnancy in the placenta definite morphological changes were observed; marked atrophy of the syntitial layer was followed by hyperplasia of the cytotrophoblastie cells. The most expressed changes occurred in the vessel wall: swelling of the endothelium, narrowing of the vessel-lumen, deposition of filamentous material in the cytoplasma. Morphological changes in the placenta in diabetes are moderate as compared to those observed in toxemia. Thickening of the basal membrane seems to be most characteristic. Ultrastructural changes are almost identical to those observed in toxemia. Morphological changes revealed may be responsible for the insufficiency of the placenta and the intrauterine damage to the foetus.
本文描述了妊娠中毒症和糖尿病患者胎盘的超微结构变化。在妊娠中毒症患者的胎盘中，观察到了明确的形态学变化；合体层明显萎缩，随后细胞滋养层细胞增生。最明显的变化发生在血管壁：内皮细胞肿胀、血管腔狭窄、细胞质中出现丝状物质沉积。与妊娠中毒症相比，糖尿病患者胎盘的形态学变化较为轻微。基底膜增厚似乎是最典型的特征。超微结构变化与妊娠中毒症中观察到的几乎相同。所揭示的形态学变化可能是胎盘功能不全和胎儿宫内损伤的原因。
