Altin Timucin, Guldal Muharrem, Candemir Basar, Polat Cegerhun, Ozdemir Aydan O, Tulunay Cansin, Ozdol Cagdas, Akyurek Omer, Karaoguz Remzi, Erol Cetin
Ankara University School of Medicine, Department of Cardiology, Ankara, Turkey.
Ann Noninvasive Electrocardiol. 2008 Oct;13(4):332-40. doi: 10.1111/j.1542-474X.2008.00243.x.
Atrial undersensing (AUS) in single-lead VDD pacemakers may be due to diminished P-wave amplitude secondary to local inflammation beneath the electrodes closer to atrial wall. The aim of this study was to assess the potential effect of distance between atrial electrode and atrial wall on immediate and long-term atrial sensing stability in VDD systems.
A total of 275 patients with normal sinus node function who received VDD pacemakers were enrolled into the study and were followed up for a median duration of 33 months. During each control visit, a standard 12-lead electrocardiogram (ECG) was obtained and standard pacemaker function assessment was performed including testing for pacing threshold and atrioventricular synchrony. The distance between atrial electrode and atrial wall was measured from chest X-ray.
Of the 275 patients, AUS was detected in 59 patients. Univariate predictors of AUS were use of closely spaced bipolar ring atrial electrode (CSBR) (P = 0.01), wider atrial ring-spacing (P = 0.03), and atrial sensitivity programmed to a higher level (P = 0.001). Use of CSBR (P = 0.04) and atrial sensitivity > or =0.3 mV (P = 0.02) were observed to be the independent predictors for AUS. When the distance between atrial electrode and atrial wall was <7 mm, AUS was less with diagonally arranged bipolar ring electrodes (DABR) than it was with CSBRs (P = 0.02).
The distance between atrial electrode and atrial wall does not appear to affect AUS incidence in VDD pacemakers. For VDD electrodes closer to atrial wall, AUS was significantly less likely in DABR-type electrodes.
单腔VDD起搏器的心房感知不足(AUS)可能是由于靠近心房壁的电极下方局部炎症导致P波振幅降低所致。本研究的目的是评估VDD系统中心房电极与心房壁之间的距离对心房感知的短期和长期稳定性的潜在影响。
共有275例窦性心律正常且接受VDD起搏器治疗的患者纳入本研究,并进行了为期33个月的随访。每次随访时,均记录标准12导联心电图(ECG),并进行标准的起搏器功能评估,包括起搏阈值和房室同步性测试。通过胸部X线测量心房电极与心房壁之间的距离。
275例患者中,59例检测到AUS。AUS的单因素预测因素包括使用近距离双极环形心房电极(CSBR)(P = 0.01)、较宽的心房环间距(P = 0.03)以及将心房感知灵敏度设置为较高水平(P = 0.001)。使用CSBR(P = 0.04)和心房感知灵敏度≥0.3 mV(P = 0.02)是AUS的独立预测因素。当心房电极与心房壁之间的距离<7 mm时,对角排列的双极环形电极(DABR)的AUS发生率低于CSBR(P = 0.02)。
心房电极与心房壁之间的距离似乎不影响VDD起搏器的AUS发生率。对于更靠近心房壁的VDD电极,DABR型电极发生AUS的可能性显著降低。