A survey of the available literature on the role of cyclic nucleotides (cyclic adenosine 3,5-monophosphate and cyclic guanosine 3,5-monophosphate) in the control over various aspects of cellular activity: regulation of growth and morphology of normal and tumorous cells, participation in differentiation of cells, blast-transformation, regulation of inflammatory and immunological processes governed by lymphocytes, is presented. A presumable mechanism of action of cyclic nucleotides is considered.
本文综述了关于环核苷酸(3,5-环磷酸腺苷和3,5-环磷酸鸟苷)在控制细胞活动各个方面所起作用的现有文献:正常细胞和肿瘤细胞的生长与形态调节、细胞分化参与、原始细胞转化、淋巴细胞主导的炎症和免疫过程调节。文中还探讨了环核苷酸可能的作用机制。