Department of Medical Psychology and Institute for Clinical and Experimental Neurosciences, VU University Medical Center, Amsterdam, The Netherlands.
Fertil Steril. 2009 Dec;92(6):1907-14. doi: 10.1016/j.fertnstert.2008.09.026. Epub 2008 Oct 29.
To evaluate the psychosocial well-being of 9-18-year-old IVF children. IVF alters fetal programming, with consequences for physical functioning. This also may apply to behavior. Behavior and socioemotional functioning of children born after IVF and spontaneously from parents with former fertility problems were studied, to control for parental factors and investigate the role of IVF on the children's functioning.
Child Behavior CheckList (CBCL) and Teacher Report Form (TRF) reports of 139 IVF and 143 control children.
VU University Medical Center, Amsterdam.
SUBJECT(S): Children's age ranged from 9 to 18 years; mean age 13.60 (+/-2.12) years in IVF and 13.51 (+/-2.11) years in controls.
MAIN OUTCOME MEASURE(S): Child's behavior and socioemotional functioning reported by parents (CBCL) and teachers (TRF).
RESULT(S): The CBCL and TRF mean scores were within the normal range. Scores of IVF parents versus controls were lower on the total problems scale, externalizing scale and syndrome scales thought problems, attention problems, aggressive and rule-breaking behavior. Less IVF children had scores in the borderline/clinical range on these scales. On the TRF, a tendency was found for lower scores on the externalizing scale in IVF children compared with controls. More IVF children scored in the borderline/clinical range on the syndrome scale withdrawn/depressed behavior.
CONCLUSION(S): Overall, behavior, and socioemotional functioning of 9-18-year-old IVF children is normal. The reduced behavior of externalizing nature reported by the parents, and teacher ratings of more withdrawn/depressed behavior need further study.
评估 9-18 岁试管婴儿儿童的心理社会幸福感。试管婴儿改变了胎儿的编程，对身体功能产生影响。这也可能适用于行为。本研究旨在研究试管婴儿和父母曾有生育问题的自然受孕儿童的行为和社会情感功能，以控制父母因素，并调查试管婴儿对儿童功能的作用。
139 名试管婴儿和 143 名对照组儿童的儿童行为检查表（CBCL）和教师报告表（TRF）报告。
阿姆斯特丹 VU 大学医学中心。
儿童年龄 9-18 岁，平均年龄 13.60（+/-2.12）岁的试管婴儿和 13.51（+/-2.11）岁的对照组。
父母（CBCL）和教师（TRF）报告的儿童行为和社会情感功能。
CBCL 和 TRF 的平均得分均在正常范围内。试管婴儿组父母与对照组相比，总问题量表、外化量表和综合征量表（包括思维问题、注意力问题、攻击和破坏行为）的得分较低。较少的试管婴儿儿童在这些量表上的得分处于边界/临床范围。在 TRF 上，与对照组相比，试管婴儿儿童的外化量表得分较低，有一定的趋势。更多的试管婴儿儿童在退缩/抑郁行为的综合征量表上得分处于边界/临床范围。
总体而言，9-18 岁试管婴儿儿童的行为和社会情感功能正常。父母报告的外化行为减少，以及教师对更多退缩/抑郁行为的评分需要进一步研究。
