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Reactions of 3-aminopyrazole derivatives with cyanothioacetamide and its derivatives: Synthesis and reactions of several new pyrazole and pyrazole[3,2-b]pyrimidine derivatives.

作者信息

Attaby F A, Eldin S M

机构信息

Department of Chemistry, Faculty of Science, Cairo University, Giza, A.R. Egypt.

出版信息

Arch Pharm Res. 1997 Aug;20(4):330-7. doi: 10.1007/BF02976195.

DOI:10.1007/BF02976195
PMID:18975174
Abstract

Thiocarboxamidocinnamonitrile derivatives2 a-f reacted with 3-aminopyrazole derivatives3 a-c to give the pyrazole[3,2-b]pyrimidine derivatives6 a-p. Compounds6 a-p were used as starting material for syntheses of several heterocylic coompounds. Dehydrogenation of6 gave pyrazole[3,2-b]pyrimidines10 a-d while its reaction with diethyl oxalate gave11. Reactions of6 with formic acid gave pyrazolopyrimidines17 a-j, and pyrazolopyrimidopyrimidinoes18 a-j.

摘要

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