Pohl Christopher, Saini Charanjit
Dionex Corp., Sunnyvale, CA 94088, USA.
J Chromatogr A. 2008 Dec 5;1213(1):37-44. doi: 10.1016/j.chroma.2008.10.072. Epub 2008 Oct 22.
We have developed a number of new anion exchange stationary phases based on synthesis of hyperbranched condensation polymers prepared in situ on surface sulfonated wide pore, low surface area ethylvinylbenzene-divinylbenzene substrate beads. These new stationary phases are synthesized by exposing the substrate beads to a mixture containing one of several different diepoxides and methyl amine followed by exposure in an alternating fashion to diepoxide and then methyl amine in a repetitive manner. With each cycle of reaction with first diepoxide and then methyl amine, the capacity of the stationary phase doubles, allowing for the synthesis of high-capacity materials. These new phases are stable to hydrolysis in concentrated acid and base. They exhibit exceptionally low levels of hydrophobic interaction with anionic species commonly of interest in the analysis of environmental samples.
我们基于在表面磺化的大孔、低表面积乙基乙烯基苯 - 二乙烯基苯基质珠粒上原位制备的超支化缩聚物合成，开发了多种新型阴离子交换固定相。这些新型固定相的合成方法是，将基质珠粒暴露于含有几种不同二环氧化物之一和甲胺的混合物中，然后以交替方式依次重复暴露于二环氧化物和甲胺。每经过一次先与二环氧化物反应然后与甲胺反应的循环，固定相的容量就会翻倍，从而能够合成高容量材料。这些新相在浓酸和浓碱中对水解稳定。它们与环境样品分析中常见的阴离子物种表现出极低水平的疏水相互作用。
