Raj V, Haman K L, Raj S R, Byrne D, Blakely R D, Biaggioni I, Robertson D, Shelton R C
Department of Psychiatry, Vanderbilt University School of Medicine, 1500 21st Ave, South, Nashville, TN 37212, USA.
J Neurol Neurosurg Psychiatry. 2009 Mar;80(3):339-44. doi: 10.1136/jnnp.2008.144360. Epub 2008 Oct 31.
Patients with postural tachycardia syndrome (POTS) often appear anxious and report inattention. Patients with POTS were formally assessed for psychiatric disorders and inattention and compared with patients with attention deficit hyperactivity disorder (ADHD) and control subjects.
Patients with POTS (n = 21), ADHD (n = 18) and normal control subjects (n = 20) were assessed for DSM-IV psychiatric disorders and completed a battery of questionnaires that assessed depression, anxiety and ADHD characteristics.
Patients with POTS did not have an increased prevalence of major depression or anxiety disorders, including panic disorder, compared with the general population. Patients with POTS had mild depression. They scored as moderately anxious on the Beck Anxiety Inventory but did not exhibit a high level of anxiety sensitivity. Patients with POTS scored significantly higher on inattention and ADHD subscales than control subjects. These symptoms were not present during childhood.
Patients with POTS do not have an increased lifetime prevalence of psychiatric disorders. Although they may seem anxious, they do not have excess cognitive anxiety. They do experience significant inattention which may be an important source of disability.
体位性心动过速综合征(POTS)患者常表现出焦虑且注意力不集中。对POTS患者进行了精神疾病及注意力不集中方面的正式评估,并与注意缺陷多动障碍(ADHD)患者及对照受试者进行比较。
对POTS患者(n = 21)、ADHD患者(n = 18)和正常对照受试者(n = 20)进行了DSM-IV精神疾病评估,并完成了一系列评估抑郁、焦虑和ADHD特征的问卷。
与普通人群相比,POTS患者中重度抑郁或焦虑障碍(包括惊恐障碍)的患病率并未增加。POTS患者有轻度抑郁。他们在贝克焦虑量表上的得分显示为中度焦虑,但未表现出高度的焦虑敏感性。POTS患者在注意力不集中和ADHD分量表上的得分显著高于对照受试者。这些症状在儿童期并不存在。
POTS患者一生中精神疾病的患病率并未增加。尽管他们可能看起来焦虑,但并无过度的认知焦虑。他们确实存在明显的注意力不集中,这可能是导致残疾的一个重要原因。