Shalybkova O P, Sokolov M V
Anesteziol Reanimatol. 1991 May-Jun(3):40-3.
Changes in hemodynamics, reserve capacities of intact and damaged myocardium have been studied, with the left and right ventricular functions during mounting volume load assessed separately. It has been shown that exclusion of the part of left ventricular myocardium from contraction deteriorated considerably the pump and contractile function not only of the left but also of the right intact heart ventricle. Heart failure in volume overload manifests itself primarily in the right ventricle and depends on the functional heart reverse on the whole: in animals with partial injury of left ventricular myocardium heart failure developed in much lower volume loads than in intact animals. In circulation volume overload, left or right ventricular stroke work index to preload or filling pressure in the corresponding heart chamber ratio was most adequate and prognostically valuable for the detection of latent heart failure.
研究了血流动力学变化、完整和受损心肌的储备能力,并分别评估了在逐渐增加容量负荷时左、右心室功能。结果表明,排除左心室心肌的一部分收缩,不仅会使左心室,而且会使右心室完整心脏的泵血和收缩功能显著恶化。容量超负荷引起的心力衰竭主要表现在右心室,并且总体上取决于心脏的功能逆转:在左心室心肌部分损伤的动物中,与完整动物相比,在低得多的容量负荷下就会发生心力衰竭。在循环容量超负荷时,左或右心室每搏功指数与相应心腔的前负荷或充盈压之比,对于检测潜在心力衰竭最为合适且具有预后价值。