一名62岁女性，自发出现明显的行走障碍和全血细胞减少症

[A 62 year old woman with spontaneous onset of distinct walking disorder and pancytopenia].

作者信息

Austein T, Badge S, Kerstan H, von Bloh J, Aue G, Lösekann M, Pacholik L

机构信息

Abteilung für Hämatologie/intern. Onkologie, Medizinische Klinik II, St. Bernhard Hospital, Brake, Deutschland.

出版信息

Internist (Berl). 2008 Dec;49(12):1512-5. doi: 10.1007/s00108-008-2248-z.

DOI:10.1007/s00108-008-2248-z

PMID:18979078

Abstract

Our case-report presents a 62 year old woman with spontaneous onset of a distinct walking disorder and pancytopenia. The diagnosis showed a sub-acute combined degeneration of the spinal cord (SACD) and a megaloblastic anemia as a result of a cobalamin deficiency. This was caused by a strict vegetarian nutrition since 18 years. Once on therapy with cobalamin substitutes the clinical and laboratory test results improved within 3 months.

摘要

我们的病例报告介绍了一位62岁女性，她自发出现明显的行走障碍和全血细胞减少。诊断显示为脊髓亚急性联合变性（SACD）以及由于钴胺素缺乏导致的巨幼细胞贫血。这是由18年来严格的素食营养引起的。一旦开始使用钴胺素替代疗法，临床和实验室检查结果在3个月内得到改善。