体外融合巨噬细胞的方法。

Methods to fuse macrophages in vitro.

作者信息

Vignery Agnès

机构信息

Department of Orthopaedics, Yale University, New Haven, CT, USA.

出版信息

Methods Mol Biol. 2008;475:383-95. doi: 10.1007/978-1-59745-250-2_22.

DOI:10.1007/978-1-59745-250-2_22

PMID:18979256

Abstract

Macrophages are mononucleate cells that fuse in rare and specific instances to form osteoclasts in bone or giant cells in chronic inflammatory conditions. Because of the central role these cells play in bone metabolism and in inflammation, respectively, methods to study their formation in vitro are described.

摘要

巨噬细胞是单核细胞，在罕见且特定的情况下会融合，在骨骼中形成破骨细胞，或在慢性炎症条件下形成巨细胞。由于这些细胞分别在骨代谢和炎症中发挥核心作用，本文描述了体外研究它们形成的方法。