Chammas E, Vaksmann G, Kacet S, Rey C, Brevière G M, el Kohen M, Dupuis C
Service de cardiologie infantile, Hôpital Cardiologique de Lille.
Arch Mal Coeur Vaiss. 1991 May;84(5):659-64.
Twenty-four patients with isolated congenital heart block were investigated by 24-hour Holter monitoring at an average age of 9.3 +/- 5.5 years. Six patients were symptomatic and 18 were asymptomatic. Eight asymptomatic patients underwent exercise stress tests and an atropine test was performed in 10 asymptomatic patients to evaluate the capacity to accelerate the heart rate. The symptomatic patients were older than the asymptomatic patients. None of the parameters which analyse ventricular rate were significantly different in the two groups of patients. Significant ventricular arrhythmias (Lown Grade 2 or over) were recorded in 1 symptomatic and 3 asymptomatic patients. The incidence of these ventricular arrhythmias increased with age and degree of bradycardia. The percentage increase in ventricular rate after atropine correlated with what was observed on effort (r = 0.95, p = 0.01) but there was no relationship between the ventricular rates during these two tests and those recorded on Holter monitoring. The results of this series of children with isolated congenital heart block show the Holter parameters cannot distinguish symptomatic from asymptomatic patients. The exercise stress and atropine tests gave very similar results but their prognostic value has not yet been established.
对24例孤立性先天性心脏传导阻滞患者进行了24小时动态心电图监测,平均年龄为9.3±5.5岁。6例有症状,18例无症状。8例无症状患者进行了运动负荷试验,10例无症状患者进行了阿托品试验,以评估心率加快的能力。有症状的患者比无症状的患者年龄大。两组患者分析心室率的各项参数均无显著差异。1例有症状患者和3例无症状患者记录到显著室性心律失常(洛恩分级2级或以上)。这些室性心律失常的发生率随年龄和心动过缓程度增加。阿托品后心室率的增加百分比与运动时观察到的情况相关(r = 0.95,p = 0.01),但这两项试验期间的心室率与动态心电图监测记录的心室率之间没有关系。这一系列孤立性先天性心脏传导阻滞儿童的结果表明,动态心电图参数无法区分有症状和无症状患者。运动负荷试验和阿托品试验结果非常相似,但其预后价值尚未确定。