Grinneiser D, Bottasso B, Benoit P, Mariani R
Cardiologie infantile, Nice.
Arch Mal Coeur Vaiss. 1991 May;84(5):727-32.
Fifteen children and adolescents with muscular dystrophy underwent investigation by Doppler echocardiography and high amplification electrocardiography to evaluate the quality of left ventricular function. High amplification ECG showed minor intra-atrial conduction defects in 3 cases and abnormal late micro potentials without arrhythmogenic late potentials in 3 other cases. Significant abnormalities were observed in 40% of children examined. Doppler echocardiography showed relative conservation of systolic left ventricular function but a decrease in indices of contractility was observed in 46% of cases, especially in patients with Duchenne muscular dystrophy. Abnormalities of left ventricular distensibility were observed earlier and were more common (53% of cases). A significant decrease in cardiac output was found in 50% of patients, especially among the older and more severely affected children irrespective of the type of muscular dystrophy. These two investigations provide complementary information for the evaluation of left ventricular function of children with muscular dystrophy and they are proposed routinely for the follow-up of these patients.
15名患有肌肉萎缩症的儿童和青少年接受了多普勒超声心动图和高放大率心电图检查，以评估左心室功能质量。高放大率心电图显示，3例存在轻微心房内传导缺陷，另外3例存在异常晚期微电位但无致心律失常晚期电位。在40%接受检查的儿童中观察到显著异常。多普勒超声心动图显示左心室收缩功能相对保留，但46%的病例观察到收缩性指标下降，尤其是杜氏肌营养不良症患者。左心室扩张性异常出现得更早且更常见（53%的病例）。50%的患者心输出量显著下降，尤其是年龄较大且病情较重的儿童，无论肌肉萎缩症的类型如何。这两项检查为评估肌肉萎缩症患儿的左心室功能提供了补充信息，建议对这些患者进行常规随访。
