Pillière R, Luquel L, Brun D, Jault F, Gandjbakhch I, Bourdarias J P
Service de cardiologie, hôpital Ambroise-Paré, Boulogne.
Arch Mal Coeur Vaiss. 1991 Jun;84(6):869-72.
Coronary artery disease (CAD) is a well-known complication of mediastinal irradiation. We report a case of subocclusive ostial stenosis of the left main coronary artery, in a 27 years old man, who had been irradiated 14 years before for a stage 4 Hodgkin's disease. Among the 68 reported cases of CAD attributed to radiotherapy, 11 involved an ostial stenosis of either right coronary artery, or left main coronary artery or both. Thus mediastinal irradiation seems to be a definite cause of ostial coronary artery stenosis; several types of myocardial revascularization have been suggested for this kind of CAD.
冠状动脉疾病(CAD)是纵隔放疗众所周知的并发症。我们报告一例27岁男性左主干冠状动脉亚闭塞性开口狭窄病例,该患者14年前因IV期霍奇金病接受过放疗。在报道的68例归因于放疗的CAD病例中,11例涉及右冠状动脉、左主干冠状动脉或两者的开口狭窄。因此,纵隔放疗似乎是冠状动脉开口狭窄的明确病因;针对这类CAD已提出了几种心肌血运重建方法。