Eberhard Stephan, Finazzi Giovanni, Wollman Francis-André
Université Pierre et Marie Curie, Institut de Biologie Physico-Chimique, F-75005 Paris, France.
Annu Rev Genet. 2008;42:463-515. doi: 10.1146/annurev.genet.42.110807.091452.
Despite recent elucidation of the three-dimensional structure of major photosynthetic complexes, our understanding of light energy conversion in plant chloroplasts and microalgae under physiological conditions requires exploring the dynamics of photosynthesis. The photosynthetic apparatus is a flexible molecular machine that can acclimate to metabolic and light fluctuations in a matter of seconds and minutes. On a longer time scale, changes in environmental cues trigger acclimation responses that elicit intracellular signaling between the nucleo-cytosol and chloroplast resulting in modification of the biogenesis of the photosynthetic machinery. Here we attempt to integrate well-established knowledge on the functional flexibility of light-harvesting and electron transfer processes, which has greatly benefited from genetic approaches, with data derived from the wealth of recent transcriptomic and proteomic studies of acclimation responses in photosynthetic eukaroytes.
尽管近期已阐明了主要光合复合物的三维结构，但我们对植物叶绿体和微藻在生理条件下光能转换的理解仍需要探索光合作用的动态过程。光合装置是一种灵活的分子机器，能够在几秒到几分钟内适应代谢和光照波动。在更长的时间尺度上，环境信号的变化会触发适应性反应，引发细胞核-细胞质与叶绿体之间的细胞内信号传导，从而导致光合机器生物发生的改变。在这里，我们试图将关于光捕获和电子传递过程功能灵活性的成熟知识（这在很大程度上得益于遗传学方法）与从近期对光合真核生物适应性反应的大量转录组学和蛋白质组学研究中获得的数据相结合。
