Perlson Eran, Holzbaur Erika L F
Department of Physiology, University of Pennsylvania School of Medicine, D400 Richards Building, 3700 Hamilton Walk, Philadelphia, PA, 19104-6085, USA.
Cell. 2008 Oct 31;135(3):414-5. doi: 10.1016/j.cell.2008.10.013.
The induction of long-term potentiation (LTP) leads to an increase in the density of AMPA receptors at dendritic spines. New work by Wang et al. (2008) reveals the mechanism by which myosin Vb regulates the intracellular trafficking of AMPA receptors from recycling endosomes to synaptic sites during LTP.
长时程增强（LTP）的诱导会导致树突棘处AMPA受体密度增加。Wang等人（2008年）的新研究揭示了肌球蛋白Vb在LTP过程中调节AMPA受体从回收内体到突触位点的细胞内运输的机制。
