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心肌脂肪酸成像在终末期肾病患者中的临床应用价值

Clinical utility of myocardial fatty acid imaging in patients with end-stage renal disease.

作者信息

Nishimura Masato, Ono Toshihiko

机构信息

Cardiovascular Division, Toujinkai Hospital, Fushimi-ku, Kyoto, Japan.

出版信息

J Nucl Cardiol. 2008 Nov-Dec;15(6):830-7. doi: 10.1007/BF03007365. Epub 2008 Sep 16.

Abstract

The prevalence of coronary artery disease (CAD) appears to be much higher in patients with end-stage renal disease (ESRD) undergoing dialysis than in a non-ESRD population. Cardiac death due to myocardial ischemia significantly contributes to the high mortality rate of ESRD patients. However, the method for screening for CAD in ESRD patients has not been established, because the frequency of silent myocardial ischemia is high and examinations requiring stress are often difficult to perform among this population. Myocardial fatty acid imaging may be a new modality to detect myocardial ischemia and identify the group at high risk for cardiac death among ESRD patients without adding any stress.

摘要

与非终末期肾病(ESRD)人群相比,接受透析的终末期肾病(ESRD)患者中冠状动脉疾病(CAD)的患病率似乎要高得多。心肌缺血导致的心脏死亡显著促成了ESRD患者的高死亡率。然而,由于无症状心肌缺血的发生率很高,且该人群往往难以进行需要负荷的检查,因此尚未确立ESRD患者中CAD的筛查方法。心肌脂肪酸成像可能是一种新的检测心肌缺血的方法,并且能够在不增加任何负荷的情况下识别ESRD患者中发生心脏死亡的高危人群。

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