Lubicz Boris, Bruneau Michaël, Dewindt Aloys, Lefranc Florence, Balériaux Danielle, De Witte Olivier
Department of Neuroradiology, Erasme University Hospital, Brussels, Belgium.
Neuroradiology. 2009 Feb;51(2):99-102. doi: 10.1007/s00234-008-0474-7. Epub 2008 Nov 5.
Aneurysms of the proximal segment of the anterior cerebral artery (A1A) are rare and challenging to treat. No information is available regarding their management by endovascular approach. The aim of this study was to report our experience with endovascular treatment (EVT) of A1As.
A retrospective review of our prospectively maintained database identified all A1As treated in our institution. The clinical charts, procedural data, and angiographic results were reviewed.
From April 2004 to August 2008, eight patients were identified and presented with an unruptured A1A. All aneurysms but one were <3 mm in diameter and two aneurysms had a perforator at the neck. Surgery was performed in two patients with an aneurysm <2 mm. Six patients were treated by selective embolization including five patients with balloon-assisted coiling (BAC) and/or via a retrograde approach from the contralateral side through the anterior communicating artery. These adjunctive techniques were used to safely catheterize the sac or to protect a branch at the neck. All patients showed an excellent clinical outcome. A complete aneurysm occlusion was obtained in all but one patient. Follow-up imaging in four patients showed stable results.
EVT of A1As is feasible and associated with good clinical and anatomical results. Because of their location, small size, and close relationship with perforators, EVT frequently requires the use of BAC and/or a retrograde approach. Our results suggest that EVT is an alternative therapeutic option to surgical clipping if the aneurysm size is compatible with selective embolization.
大脑前动脉近端段(A1A)动脉瘤较为罕见,治疗具有挑战性。目前尚无关于其血管内治疗的相关信息。本研究旨在报告我们对A1A进行血管内治疗(EVT)的经验。
对我们前瞻性维护的数据库进行回顾性分析,确定了在我们机构接受治疗的所有A1A。对临床病历、手术数据和血管造影结果进行了审查。
2004年4月至2008年8月,共确定8例未破裂的A1A患者。除1例动脉瘤外,其余所有动脉瘤直径均<3 mm,2例动脉瘤颈部有穿支。2例直径<2 mm的动脉瘤患者接受了手术治疗。6例患者接受了选择性栓塞治疗,其中5例采用球囊辅助弹簧圈栓塞(BAC)和/或通过前交通动脉从对侧逆行入路。这些辅助技术用于安全地将导管插入瘤腔或保护颈部分支。所有患者临床结局良好。除1例患者外,其余患者动脉瘤均完全闭塞。4例患者的随访影像学检查结果稳定。
A1A的EVT是可行的,且临床和解剖学效果良好。由于其位置、体积小以及与穿支关系密切,EVT通常需要使用BAC和/或逆行入路。我们的结果表明,如果动脉瘤大小适合选择性栓塞,EVT是手术夹闭的一种替代治疗选择。