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在沙子存在的情况下氨基酸的热聚合反应。

The thermal polymerization of amino acids in the presence of sand.

作者信息

Rohlfing D L, McAlhaney W W

出版信息

Biosystems. 1976 Dec;8(3):139-45. doi: 10.1016/0303-2647(76)90016-2.

DOI:10.1016/0303-2647(76)90016-2
PMID:189854
Abstract

Sand was tested as a model of a common "impurity" that could have influenced the formation of thermal prebiotic protein. Increasing proportions of sand (0-16 g) in admixture with one set of reactant amino acids (1g), when heated at 175 degrees C for 1.5 h, resulted in increasing yields of polyamino acids of increasing size and color intensity; amino acid composition was not greatly affected. Similar results were noted for three of five other sets of reactant amino acids (8 g sand per g amino acids). In no case did sand prevent the amino acids from polymerizing. The results are interpreted to indicate a broader range of conditions conducive to the formation of prebiotic protein and to further emphasize that environmental parameters should be considerided in the experimental modeling of prebiotic processes.

摘要

沙子作为一种可能影响热前生物蛋白质形成的常见“杂质”模型进行了测试。将沙子(0 - 16克)与一组反应物氨基酸(1克)混合,在175摄氏度下加热1.5小时,随着沙子比例增加,多氨基酸的产量增加,其大小和颜色强度也增加;氨基酸组成受影响不大。对于其他五组反应物氨基酸中的三组(每克氨基酸8克沙子)也观察到了类似结果。在任何情况下,沙子都没有阻止氨基酸聚合。这些结果被解释为表明有利于前生物蛋白质形成的条件范围更广,并进一步强调在模拟前生物过程的实验中应考虑环境参数。

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引用本文的文献

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Which amino acids should be used in prebiotic chemistry studies?益生元化学研究中应使用哪些氨基酸?
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Silica, alumina and clay catalyzed peptide bond formation: enhanced efficiency of alumina catalyst.二氧化硅、氧化铝和粘土催化肽键形成:氧化铝催化剂效率提高
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Adsorption of small biological molecules on silica from diluted aqueous solutions: quantitative characterization and implications to the Bernal's hypothesis.
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Synthesis of peptides from amino acids and ATP with lysine-rich proteinoid.由氨基酸和ATP与富含赖氨酸的类蛋白质合成肽。
J Mol Evol. 1980 May;15(2):161-8. doi: 10.1007/BF01732668.
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Growth of peptide chains on silica in absence of amino acid access from without.在没有外部氨基酸供应的情况下,肽链在二氧化硅上的生长。
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