Kennedy W F, Gruen T A, Chessin H, Gasparini G, Thompson W
Theda Clark Regional Medical Center, Neenah, Wisconsin.
Clin Orthop Relat Res. 1991 Jan(262):185-91.
Clinical and roentgenographic observations on a postoperative low-dose radiation of 1000 cGy for prevention of heterotopic ossification in high-risk patients after 48 noncemented total hip arthroplasties demonstrated no overall statistical difference in the Harris hip scores between the treated group (92.2) and the control group (91.0). There was no difference in the incidence of radiolucent lines about the components, and there were no revisions for aseptic loosening in the treated group. The incidence of clinically significant (Brooker Grades III and IV) heterotopic bone formation was lower in the treated group (7%) than in the control group (32%). This difference in the incidence of heterotopic bone formation was statistically significant. Radiation therapy was effective in preventing postoperative heterotopic bone formation in biologically fixed total hip implants.
对48例非骨水泥型全髋关节置换术后的高危患者进行1000厘戈瑞的术后低剂量放疗以预防异位骨化的临床和X线观察显示,治疗组(92.2)和对照组(91.0)的Harris髋关节评分在总体上无统计学差异。假体周围透亮线的发生率无差异,治疗组无因无菌性松动而翻修的病例。治疗组临床上显著(布鲁克分级III级和IV级)异位骨形成的发生率(7%)低于对照组(32%)。异位骨形成发生率的这种差异具有统计学意义。放射治疗对预防生物固定型全髋关节假体术后异位骨形成有效。