Cordier G, Rouprêt M, Berthier R, Michel P-L, Haab F, Cussenot O, Beley S
Service d'urologie, hôpital Tenon, Assistance publique-Hôpitaux de Paris, groupe hospitalo-universitaire Est, faculté de médecine Pierre-et-Marie-Curie, université Paris-6, 4, rue de la Chine, 75020 Paris, France.
Prog Urol. 2008 Oct;18(9):595-600. doi: 10.1016/j.purol.2008.06.007. Epub 2008 Sep 2.
To study prevalence and severity of erectile dysfunction (ED) in a population of men treated in emergency for a coronaropathy.
The files of 200 patients who underwent a coronarography in urgency before the 1st of January 2007 were reviewed retrospectively. The following data were collated: epidemiological data and detailed breakdown of affected coronary arteries. The following patients were excluded from the current study: age over 65, past history of prostate surgery or pelvic external beam radiation therapy. The international index of erectile function (IIEF-5) questionnaire was sent by regular mail. Patients were classified according to the severity of ED: "no ED" between 21 and 25 inclusive, "mild ED" less than 21, "moderate ED" less than 17 and "strong ED" less than 10.
Overall, 78 patients were included with a median age of 58 years. Prevalence of DE was 0.82 and median length of evolution was 9 months before coronary syndrome. Forty-nine patients (62.8%) had an ED classified between moderate and strong. ED was significantly associated with the group of patients smoking more than 20 cigarettes a day for at least 10 years (N = 44; P = 0.01) and with the group of patients older than 60 years (N = 38; P = 0.02). There was an association between the severity of the coronary disease and an ED classified between moderate and strong (P = 0.03).
This study corroborates the existence of a strong link between ED and coronary disease, notably in patients under 65 years of age. In addition, it seems that the severity of ED is directly related with the anatomical severity of coronary disease.
研究因冠心病接受急诊治疗的男性人群中勃起功能障碍(ED)的患病率及严重程度。
回顾性分析2007年1月1日前接受急诊冠状动脉造影的200例患者的病历。整理了以下数据:流行病学数据及受累冠状动脉的详细分类。以下患者被排除在本研究之外:年龄超过65岁、有前列腺手术或盆腔外照射放疗史。通过普通邮件发送国际勃起功能指数(IIEF - 5)问卷。根据ED的严重程度对患者进行分类:“无ED”为21至25分(含21和25分),“轻度ED”小于21分,“中度ED”小于17分,“重度ED”小于10分。
总体而言,纳入78例患者,中位年龄为58岁。ED的患病率为0.82,冠状动脉综合征出现前的中位病程为9个月。49例患者(62.8%)的ED分类为中度至重度。ED与每天吸烟超过20支且至少持续10年的患者组(N = 44;P = 0.01)以及年龄超过60岁的患者组(N = 38;P = 0.02)显著相关。冠心病的严重程度与分类为中度至重度的ED之间存在关联(P = 0.03)。
本研究证实了ED与冠心病之间存在紧密联系,尤其是在65岁以下的患者中。此外,ED的严重程度似乎与冠心病的解剖学严重程度直接相关。