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用于膝骨关节炎的氨基葡萄糖——有什么新进展?

Glucosamine for knee osteoarthritis--what's new?

出版信息

Drug Ther Bull. 2008 Nov;46(11):81-4. doi: 10.1136/dtb.2008.10.0025.

DOI:10.1136/dtb.2008.10.0025
PMID:18987381
Abstract

Glucosamine is a natural substance that has been widely used for several years as a food supplement to treat people with osteoarthritis.1 One formulation of black triangle downglucosamine hydrochloride (Alateris - Ransom) has recently become the first (and is currently the only) glucosamine product to be licensed as a medicine in the UK for symptomatic relief of mild to moderate osteoarthritis of the knee. In 2002, we concluded that unlicensed "oral glucosamine sulphate 1,500 mg [daily] probably provides modest symptom relief in patients with osteoarthritis of the knee and its efficacy appears similar to that of NSAIDs".1 Here we update our advice in the light of new evidence and assess the place of the licensed glucosamine hydrochloride tablets.

摘要

氨基葡萄糖是一种天然物质,作为食品补充剂用于治疗骨关节炎患者已有数年。1 一种黑色三角形标识的盐酸氨基葡萄糖制剂(Alateris - Ransom)最近成为英国首个(且目前是唯一)获得药品许可,用于缓解膝关节轻至中度骨关节炎症状的氨基葡萄糖产品。2002年,我们得出结论:未经许可的“口服硫酸氨基葡萄糖1500毫克[每日]可能为膝关节骨关节炎患者提供适度的症状缓解,其疗效似乎与非甾体抗炎药相似”。1 在此,我们根据新证据更新建议,并评估已获许可的盐酸氨基葡萄糖片剂的地位。

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1
Glucosamine for knee osteoarthritis--what's new?用于膝骨关节炎的氨基葡萄糖——有什么新进展?
Drug Ther Bull. 2008 Nov;46(11):81-4. doi: 10.1136/dtb.2008.10.0025.
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