Yokoyama Akira, Dairaku Naohiro, Kusano Masao, Koshita Shinsuke, Shimada Norihiro, Yamagiwa Tetsuya, Kojima Yasuhiro, Ojima Toshiaki, Ikeya Shinichi, Nakayama Haruo, Sugai Yoshiki, Hiwatashi Nobuo, Asano Shigeyuki
Department of Gastroenterology, Iwaki Kyoritsu General Hospital.
Nihon Shokakibyo Gakkai Zasshi. 2008 Nov;105(11):1619-26.
Case1 was a 52-year-old man who had recurrence of postoperative intra-abdominal disseminations from gastrointestinal stromal tumor (GIST) of the jejunum. Case2 was a 66-year-old man who had GIST of the jejunum with multiple liver metastases. Two cases presented hemoperitoneum caused by administration of imatinib mesylate, and we conducted emergent surgery. In spite of surgically non-curative cases, it is suggested that the surgical management for GIST of high grade group with peritoneal exposure should be followed by the administration of imatinib mesylate.
病例1是一名52岁男性，空肠胃肠道间质瘤（GIST）术后腹腔内复发转移。病例2是一名66岁男性，空肠胃肠道间质瘤伴多发肝转移。两例均因甲磺酸伊马替尼治疗导致腹腔积血，我们进行了急诊手术。尽管手术无法治愈，但对于有腹膜受累的高级别组GIST，建议在手术治疗后给予甲磺酸伊马替尼治疗。
