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使用生物合成人生长激素增强醋酸布舍瑞林/人绝经期促性腺激素对卵巢反应不良女性的排卵诱导作用。

The use of biosynthetic human growth hormone to augment ovulation induction with buserelin acetate/human menopausal gonadotropin in women with a poor ovarian response.

作者信息

Ibrahim Z H, Matson P L, Buck P, Lieberman B A

机构信息

Regional IVF Unit, Saint Mary's Hospital, Manchester, United Kingdom.

出版信息

Fertil Steril. 1991 Jan;55(1):202-4. doi: 10.1016/s0015-0282(16)54084-9.

DOI:10.1016/s0015-0282(16)54084-9
PMID:1898890
Abstract

The present study has demonstrated the usefulness of GH in augmenting buserelin acetate/hMG to stimulate the rate of growth of follicles in women regarded as poor responders. The PR achieved was extremely encouraging in a group of patients whose prognosis was otherwise poor. Further studies are required to confirm these preliminary data.

摘要

本研究已证明生长激素（GH）在增强醋酸布舍瑞林/人绝经期促性腺激素（hMG）以刺激被视为低反应者的女性卵泡生长速率方面的有效性。在一组预后原本较差的患者中所取得的妊娠率非常令人鼓舞。需要进一步的研究来证实这些初步数据。

相似文献

1
The use of biosynthetic human growth hormone to augment ovulation induction with buserelin acetate/human menopausal gonadotropin in women with a poor ovarian response.使用生物合成人生长激素增强醋酸布舍瑞林/人绝经期促性腺激素对卵巢反应不良女性的排卵诱导作用。
Fertil Steril. 1991 Jan;55(1):202-4. doi: 10.1016/s0015-0282(16)54084-9.
2
Clinical and endocrinological changes in women following ovulation induction using buserelin acetate/human menopausal gonadotrophin augmented with biosynthetic human growth hormone.
Hum Reprod. 1992 Jul;7(6):770-5. doi: 10.1093/oxfordjournals.humrep.a137735.
3
Short-term utilization of a gonadotropin-releasing hormone agonist (buserelin) for induction of ovulation in an in vitro fertilization program.在体外受精程序中短期使用促性腺激素释放激素激动剂（布舍瑞林）诱导排卵。
Ann N Y Acad Sci. 1988;541:96-102. doi: 10.1111/j.1749-6632.1988.tb22245.x.
4
Addition of Buserelin to human menopausal gonadotrophins in patients with failed stimulations for IVF or GIFT.对于体外受精（IVF）或配子输卵管内移植（GIFT）促排卵失败的患者，在人绝经期促性腺激素中添加布舍瑞林。
Hum Reprod. 1988 Oct;3 Suppl 2:35-8. doi: 10.1093/humrep/3.suppl_2.35.
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Adjuvant leuprolide in normal, abnormal, and poor responders to controlled ovarian hyperstimulation for in vitro fertilization/gamete intrafallopian transfer.在体外受精/配子输卵管内移植的控制性卵巢刺激中，正常、异常及反应不良者使用辅助性亮丙瑞林的情况。
Fertil Steril. 1989 Jun;51(6):998-1006. doi: 10.1016/s0015-0282(16)60733-1.
6
Comparison of 'poor' responders with 'good' responders using a standard buserelin/human menopausal gonadotrophin regime for in-vitro fertilization.
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Ovarian response and pregnancy rates in in vitro fertilization, gamete intrafallopian transfer, and in vivo fertilization therapies after combined gonadotropin-releasing hormone agonist/human menopausal gonadotropin stimulation.
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A controlled study of gonadotropin-releasing hormone agonist (buserelin acetate) for folliculogenesis in routine in vitro fertilization patients.促性腺激素释放激素激动剂（醋酸布舍瑞林）用于常规体外受精患者卵泡生成的对照研究。
Fertil Steril. 1991 Sep;56(3):509-14. doi: 10.1016/s0015-0282(16)54550-6.
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Hum Reprod. 1994 Aug;9(8):1421-6. doi: 10.1093/oxfordjournals.humrep.a138722.
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Serum inhibin as an index of ovarian function in women undergoing pituitary suppression and ovarian stimulation in an in vitro fertilization program.血清抑制素作为体外受精程序中接受垂体抑制和卵巢刺激的女性卵巢功能指标。
Horm Res. 1991;35(5):173-7. doi: 10.1159/000181897.

引用本文的文献

1
What Is the Best Regimen for Ovarian Stimulation of Poor Responders in ART/IVF?ART/IVF 中卵巢刺激不良反应者的最佳方案是什么？
Front Endocrinol (Lausanne). 2020 Apr 17;11:192. doi: 10.3389/fendo.2020.00192. eCollection 2020.
2
Growth Hormone Supplementation May Not Improve Live Birth Rate in Poor Responders.生长激素补充可能无法提高低反应者的活产率。
Front Endocrinol (Lausanne). 2020 Jan 23;11:1. doi: 10.3389/fendo.2020.00001. eCollection 2020.
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Management of poor responders in IVF: is there anything new?体外受精中反应不良者的管理：有什么新进展吗？
Biomed Res Int. 2014;2014:352098. doi: 10.1155/2014/352098. Epub 2014 Jul 20.
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Prediction and diagnosis of poor ovarian response: the dilemma.卵巢低反应的预测与诊断：困境
J Reprod Infertil. 2011 Oct;12(4):241-8.
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Different ovarian stimulation protocols for women with diminished ovarian reserve.针对卵巢储备功能减退女性的不同卵巢刺激方案。
J Assist Reprod Genet. 2007 Dec;24(12):597-611. doi: 10.1007/s10815-007-9181-2. Epub 2007 Nov 22.
6
Cessation of low-dose gonadotropin releasing hormone agonist therapy followed by high-dose gonadotropin stimulation yields a favorable ovarian response in poor responders.低剂量促性腺激素释放激素激动剂治疗停止后，继以高剂量促性腺激素刺激，可使低反应者产生良好的卵巢反应。
J Assist Reprod Genet. 2002 Jan;19(1):1-6. doi: 10.1023/a:1014026220880.
7
Does pretreatment with progestogen or oral contraceptive pills in low responders followed by the GnRHa flare protocol improve the outcome of IVF-ET?在低反应者中，先使用孕激素或口服避孕药进行预处理，然后采用GnRHa激发方案，是否能改善体外受精-胚胎移植（IVF-ET）的结局？
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Follicular fluid insulin-like growth factor-I and insulin-like growth factor-binding protein-1 and -3 vary as a function of ovarian reserve and ovarian stimulation.卵泡液中的胰岛素样生长因子-I、胰岛素样生长因子结合蛋白-1和-3随卵巢储备和卵巢刺激而变化。
J Assist Reprod Genet. 1998 Nov;15(10):587-93. doi: 10.1023/a:1020377209952.
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In vitro fertilization with low-dose clomiphene citrate stimulation in women who respond poorly to superovulation.对超排卵反应不良的女性采用低剂量枸橼酸氯米芬刺激进行体外受精。
J Assist Reprod Genet. 1997 Oct;14(9):503-7. doi: 10.1023/a:1021171225322.
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Growth hormone cotreatment with gonadotropins in ovulation induction.在排卵诱导中生长激素与促性腺激素联合治疗。
J Endocrinol Invest. 1996 Dec;19(11):763-79. doi: 10.1007/BF03347881.