Piotin Michel, Spelle Laurent, Mounayer Charbel, Loureiros Carolina, Ghorbani Askar, Moret Jacques
Stroke. 2009 Jan;40(1):321-3. doi: 10.1161/STROKEAHA.108.520866. Epub 2008 Nov 6.
We report our experience using Matrix coils in coiling of cerebral aneurysms.
Clinical and angiographic outcomes of 152 patients (165 aneurysms) treated exclusively with Matrix coils were retrospectively analyzed.
There were 74 ruptured aneurysms (44.8%) and 91 unruptured (55.2%). After coiling, 84 (50.9%) aneurysms were occluded, 38 (23.0%) aneurysms had a neck remnant, and 43 (26.1%) aneurysms had a sac remnant. Packing ranged from 10% to 49% (mean and median, 27%). Overall treatment-induced morbidity was 6.6% and mortality was 1.3% (10 of 152 to 2 of 152, respectively). One hundred fifteen (69.7%) aneurysms were followed, disclosing 42 (36.5%) recurrences at a mean period of 9 months (median, 6 months; range, 1 to 28 months). The recurrence rate for small aneurysms (<10 mm) was 28 (31.1%) of 90, whereas for larger aneurysms (>/=10 mm), the recurrence rate was 14 (56.0%) of 25 (P=0.0336). When packing was </=25%, the recurrence rate was 44.4%, whereas for aneurysms with packing >25%, the recurrence rate was 29.8% (P=0.1588). Recurrence rate was not correlated to packing. Ruptured aneurysms recurred more frequently than unruptured aneurysms (P=0.0004).
Matrix coils provided no better recanalization rates than those reported previously for bare platinum coils.
我们报告使用Matrix弹簧圈治疗脑动脉瘤的经验。
回顾性分析152例患者（165个动脉瘤）单纯使用Matrix弹簧圈治疗的临床及血管造影结果。
74个动脉瘤破裂（44.8%），91个未破裂（55.2%）。弹簧圈栓塞后，84个（50.9%）动脉瘤闭塞，38个（23.0%）动脉瘤有瘤颈残留，43个（26.1%）动脉瘤有瘤囊残留。填充率为10%至49%（平均和中位数为27%）。总体治疗引起的发病率为6.6%，死亡率为1.3%（分别为152例中的10例和152例中的2例）。对115个（69.7%）动脉瘤进行了随访，平均9个月（中位数6个月；范围1至28个月）时发现42个（36.5%）复发。小动脉瘤（<10mm）的复发率为90个中的28个（31.1%），而大动脉瘤（≥10mm）的复发率为25个中的14个（56.0%）（P=0.0336）。当填充率≤25%时，复发率为44.4%，而填充率>25%的动脉瘤复发率为29.8%（P=0.1588）。复发率与填充率无关。破裂动脉瘤比未破裂动脉瘤复发更频繁（P=0.0004）。
Matrix弹簧圈的再通率并不比先前报道的裸铂金弹簧圈更好。
