Halbreich U, Rojansky N, Bakhai Y, Wang K
Department of Obstetrics and Gynecology, State University of New York, Buffalo 14215.
J Clin Psychiatry. 1991 Jan;52(1):15-6.
The authors report two cases of menstrual irregularities associated with bupropion treatment. This is the first report of such an association, and it is supported by data collected by the Burroughs Wellcome Co. Since the mode of action of this effective new antidepressant is basically unknown and does not operate through any of the putative mechanisms of the classical antidepressants, its side effect profile is of heuristic as well as practical importance.
作者报告了两例与安非他酮治疗相关的月经不调病例。这是此类关联的首次报告，并且得到了宝威公司收集的数据的支持。由于这种有效的新型抗抑郁药的作用方式基本未知，且并非通过经典抗抑郁药的任何假定机制起作用，因此其副作用情况具有启发意义和实际重要性。
