Khilnani Gopi C, Banga Amit
Department of Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India.
Int J Chron Obstruct Pulmon Dis. 2008;3(3):351-7. doi: 10.2147/copd.s946.
Recent years have seen the emergence of noninvasive ventilation (NIV) as an important tool for management of patients with acute exacerbation of chronic obstructive pulmonary disease (COPD). Several well conducted studies in the recent years have established its role in the initial, as well as later management of these patients. However, some grey areas remain. Moreover, data is emerging on the role of long term nocturnal NIV use in patients with very severe stable COPD. This review summarizes the evidence supporting the use of NIV in various stages of COPD, discuss the merits as well as demerits of this novel ventilatory strategy and highlight the grey areas in the current body of knowledge.
近年来,无创通气(NIV)已成为管理慢性阻塞性肺疾病(COPD)急性加重患者的重要工具。近年来的几项精心开展的研究确立了其在这些患者初始及后续管理中的作用。然而,仍存在一些灰色地带。此外,关于长期夜间使用无创通气对极重度稳定期慢性阻塞性肺疾病患者的作用的数据也在不断涌现。本综述总结了支持在慢性阻塞性肺疾病各个阶段使用无创通气的证据,讨论了这种新型通气策略的优缺点,并突出了当前知识体系中的灰色地带。