Garcia-Jimenez Sara, Heredia-Lezama Karina, Bilbao-Marcos Fernando, Fuentes-Lara Griselda, Monroy-Noyola Antonio, Deciga-Campos Myrna
Facultad de Farmacia Universidad Autónoma del Estado de Morelos, Cuernavaca, Morelos, México.
Ann N Y Acad Sci. 2008 Oct;1139:422-5. doi: 10.1196/annals.1432.018.
Drug abuse among college students is characterized by lower academic performance and long-term negative consequences. Screening to detect students at high risk of consuming drugs is of primary importance to insure early identification and appropriate levels of care. As a result, this study aimed to determine the current or past use of drug abuse through a questionnaire applied to a student population at the Universidad Autónoma del Estado de Morelos. The results were confirmed by immunoanalysis and gas chromatography of urine. We interviewed 181 students aged 15 to 21 (gender was not considered in this study), and urine samples were collected for analytical analysis. For detection of metabolites Delta9-THCA-A and benzoylecgonine from marijuana and cocaine, respectively, a homogenous enzymatic inmmunoanalysis was used; subsequent samples were analyzed by a mass spectrometer with quadrupole detector. Seven samples of the total (181) did not completely fit the inclusion criteria and were eliminated. The results showed 0.50% and 1.16% positive samples for benzoylecgonine and Delta9-THCA-A, respectively. These results are not different from those of the National Questionnaire on Addiction. We can establish a program for detecting drug consumption in our students. This kind of study is important in order to implement programs that can help us to decrease the abuse of drugs in our college population.
大学生药物滥用的特点是学业成绩较低以及长期的负面后果。进行筛查以发现有吸毒高风险的学生对于确保早期识别和适当的护理水平至关重要。因此，本研究旨在通过对莫雷洛斯州自治大学的学生群体进行问卷调查来确定当前或过去的药物滥用情况。结果通过尿液的免疫分析和气相色谱法得到证实。我们采访了181名年龄在15至21岁之间的学生（本研究未考虑性别），并收集尿液样本进行分析。分别使用均质酶免疫分析法检测大麻和可卡因的代谢物Delta9-THCA-A和苯甲酰芽子碱；随后的样本通过带有四极杆检测器的质谱仪进行分析。总共181个样本中有7个不完全符合纳入标准，被排除。结果显示，苯甲酰芽子碱和Delta9-THCA-A的阳性样本分别为0.50%和1.16%。这些结果与全国成瘾问卷的结果没有差异。我们可以制定一个检测我校学生药物消费情况的计划。这类研究对于实施有助于减少我校学生群体药物滥用的计划非常重要。
