Urinary excretion of ganciclovir contributes to improvement of adenovirus-associated hemorrhagic cystitis after allogeneic bone marrow transplantation.
作者信息
Nakazawa Yozo, Suzuki Takefumi, Fukuyama Tetsuhiro, Katsuyama Yoshihiko, Tanaka Miyuki, Yanagisawa Ryu, Sakashita Kazuo, Shiohara Masaaki, Koike Kenichi
机构信息
Department of Pediatrics, Shinshu University School of Medicine, Matsumoto, Japan.
出版信息
Pediatr Transplant. 2009 Aug;13(5):632-5. doi: 10.1111/j.1399-3046.2008.01027.x. Epub 2008 Oct 7.
Abstract
A nine-yr-old girl developed AdV-associated HC after bone marrow transplantation. Intravenous GCV markedly reduced urinary AdV DNA loads and improved clinical findings. This appeared to result partly from a high concentration of GCV in urine. GCV may be effective for AdV-induced HC without definitive disseminated infection.
摘要
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