Canaud Ludovic, Marzelle Jean, Bassinet Laurence, Carrié Anne-Sophie, Desgranges Pascal, Becquemin Jean-Pierre
Service de Chirurgie Vasculaire, Hôpital Henri Mondor, University of Paris, XII, Créteil, France.
J Vasc Surg. 2008 Oct;48(4):1012-6. doi: 10.1016/j.jvs.2008.05.012.
Mycotic aneurysm secondary to tuberculous infection of the aorta is a rare and life-threatening disease. We report a single-center experience of three patients treated with a combination of surgical aortic replacement and prolonged antituberculosis therapy. The first case is a 34-year-old woman with a suprarenal abdominal aortic aneurysm, the second case is a 77-year-old man with an infrarenal abdominal aortic aneurysm and a right psoas abscess, the third case is a 37-year-old woman with an infrarenal abdominal aortic aneurysm. All patients had a favorable outcome with a mean follow-up of 6.2 years (range, 6 months-10 years). Early diagnosis and a combination of surgical intervention (aortic reconstruction and extensive excision of the infected field) and prolonged antituberculous drug therapy provide long-term survival without evidence of recurrence after tuberculous aortic involvement.
继发于主动脉结核感染的霉菌性动脉瘤是一种罕见且危及生命的疾病。我们报告了单中心3例患者接受主动脉置换手术联合长期抗结核治疗的经验。第一例是一名34岁女性,患有肾上腺水平腹主动脉瘤;第二例是一名77岁男性,患有肾下腹主动脉瘤和右侧腰大肌脓肿;第三例是一名37岁女性,患有肾下腹主动脉瘤。所有患者预后良好,平均随访6.2年(范围6个月至10年)。早期诊断以及手术干预(主动脉重建和感染区域广泛切除)与长期抗结核药物治疗相结合,可实现长期生存,且结核性主动脉受累后无复发迹象。