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肾上腹主动脉感染性动脉瘤。

Infected aneurysms of the suprarenal abdominal aorta.

机构信息

Department of Surgery, National Taiwan University Hospital, National Taiwan University, College of Medicine, Taipei, Taiwan.

出版信息

J Vasc Surg. 2011 Oct;54(4):972-8. doi: 10.1016/j.jvs.2011.04.024. Epub 2011 Jul 29.

DOI:10.1016/j.jvs.2011.04.024
PMID:21802245
Abstract

BACKGROUND

Infected aneurysm of the suprarenal abdominal aorta is rare and can be fatal without surgery. There have been only sporadic case reports or small case series. We review our experience with 14 patients over 13 years.

METHODS

Retrospective chart review.

RESULTS

Between 1997 and 2010, 14 cases of infected aneurysms of the suprarenal abdominal aorta were treated at our hospital. There were 11 men with median age of 75.5 years (range, 35-88). Of the 13 pathogens isolated, the most common responsible microorganism was nontyphoid Salmonella in eight (62%) followed by Staphylococcus aureus in three (23%) and Streptococcus in two patients (15%). At the first admission, six patients had medical treatment alone, five patients underwent early open in situ graft repair, and three patients underwent hybrid endovascular stenting and visceral debranching. Of the six medically treated patients, two patients died in the hospital because of aneurysm rupture, and two patients underwent late open in situ graft repair because of aneurysm progression or rupture. Of the five open surgically treated patients, one patient died in the hospital because of nosocomial sepsis, and four patients were alive without major postoperative complication. Of the three endovascularly treated patients, one patient died in the hospital because of intestinal ischemia, one patient died 6 months later because of postoperative complication, and one patient was alive with complications of paraplegia, renal failure, and permanent dialysis. The aneurysm-related mortality rate was 33% (2/6) in medical treatment alone, 20% (1/5) in open in situ grafting, and 67% (2/3) in hybrid endovascular stenting.

CONCLUSIONS

Infected aneurysm of the suprarenal abdominal aorta was rare. Nontyphoid Salmonella was the most common responsible microorganism. Open in situ graft repair remained a preferred and durable treatment strategy.

摘要

背景

肾上腹主动脉感染性动脉瘤罕见,如不手术治疗可致命。仅有零星的病例报告或小病例系列。我们回顾了 13 年来 14 例患者的经验。

方法

回顾性病历分析。

结果

1997 年至 2010 年,我院收治了 14 例肾上腹主动脉感染性动脉瘤患者。男性 11 例,中位年龄 75.5 岁(范围 35-88 岁)。在分离出的 13 种病原体中,8 例(62%)最常见的致病微生物是非伤寒沙门氏菌,3 例(23%)为金黄色葡萄球菌,2 例(15%)为链球菌。首次入院时,6 例单独接受内科治疗,5 例早期行原位开放式移植修复,3 例行杂交血管内支架和内脏去分支术。在 6 例内科治疗患者中,2 例因动脉瘤破裂死亡,2 例因动脉瘤进展或破裂行晚期原位开放式移植修复。5 例开放式手术治疗患者中,1 例因院内脓毒症死亡,4 例患者无重大术后并发症存活。3 例血管内治疗患者中,1 例因肠缺血死亡,1 例术后 6 个月死亡,1 例因截瘫、肾衰竭和永久性透析并发症存活。单纯内科治疗的动脉瘤相关死亡率为 33%(2/6),原位开放式移植的死亡率为 20%(1/5),杂交血管内支架的死亡率为 67%(2/3)。

结论

肾上腹主动脉感染性动脉瘤罕见,非伤寒沙门氏菌是最常见的致病微生物。开放式原位移植仍然是首选和持久的治疗策略。

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