Martens L L, ten Velden G H, Bol P
Abt Associates Inc., Cambridge, MA 02138-1168.
Ned Tijdschr Geneeskd. 1991 Jan 5;135(1):16-20.
In the Netherlands, Haemophilus influenzae type b (Hib) causes invasive disease in hundreds of children every year; meningitis is the most frequent and most severe infection. Children from the age of 6 months can be protected against Hib-diseases by conjugated vaccines. The financial consequences of the introduction of such vaccine into the state vaccination programme are considered in a cost-effectiveness analysis. Some elements in the analysis are still uncertain, such as the price and the schedule and method of administration of the vaccine. Presumably, the costs and benefits will be in balance, if one vaccine dose will cost about 7 US $+ and if the administration can be combined with the present programme of vaccinations against diphtheria, whooping cough, poliomyelitis and tetanus.
在荷兰，b型流感嗜血杆菌（Hib）每年导致数百名儿童罹患侵袭性疾病；脑膜炎是最常见且最严重的感染类型。6个月及以上的儿童可通过接种结合疫苗预防Hib疾病。在一项成本效益分析中，考虑了将此类疫苗纳入国家疫苗接种计划的财务影响。该分析中的一些因素仍不确定，例如疫苗的价格、接种时间表和接种方法。据推测，如果一剂疫苗成本约为7美元以上，并且接种能够与目前的白喉、百日咳、脊髓灰质炎和破伤风疫苗接种计划相结合，那么成本和效益将达到平衡。
