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肾上腺皮质癌侵犯下腔静脉:病例报告及文献复习

Adrenocortical carcinoma invading the inferior vena cava: case report and literature review.

作者信息

Mezhir James J, Song Jie, Piano Giancarlo, Testa Guiliano, Raman Jaishankar, Al-Ahmadie Hikmat A, Angelos Peter

机构信息

Department of Surgery, Sections of General Surgery, University of Chicago Medical Center, Chicago, IL 60637, USA.

出版信息

Endocr Pract. 2008 Sep;14(6):721-5. doi: 10.4158/EP.14.6.721.

DOI:10.4158/EP.14.6.721
PMID:18996792
Abstract

OBJECTIVE

To present the case of a man with a right-sided adrenocortical carcinoma that invaded the inferior vena cava and was managed by radical resection and vein patch repair.

METHODS

We report the clinical, laboratory, imaging, and operative findings, and we highlight the pertinent features of this case. The literature is reviewed for the management of adrenocortical carcinoma in conjunction with inferior vena cava invasion.

RESULTS

In a 34-year-old man with new-onset abdominal pain, abdominal imaging disclosed a large right adrenal mass with invasion into the inferior vena cava. Laboratory values revealed that the adrenal mass was likely nonfunctional. At surgical intervention with use of cardiopulmonary bypass, the mass was removed en bloc with the adrenal gland, right kidney, and the wall of the inferior vena cava, and the inferior vena cava was reconstructed with bovine pericardium.

CONCLUSION

Despite direct invasion or extension of tumor thrombus into the inferior vena cava (or both), complete (R0) resection can be obtained. Thus, this scenario should not preclude attempted curative resection in patients with adrenal cancer.

摘要

目的

介绍一例右侧肾上腺皮质癌侵犯下腔静脉并接受根治性切除及静脉补片修复治疗的病例。

方法

我们报告临床、实验室、影像学及手术 findings,并突出该病例的相关特征。回顾文献中肾上腺皮质癌合并下腔静脉侵犯的治疗方法。

结果

一名34岁新发腹痛男性,腹部影像学检查发现右侧肾上腺有一巨大肿块,侵犯下腔静脉。实验室检查结果显示肾上腺肿块可能无功能。在使用体外循环的手术干预中,肿块与肾上腺、右肾及下腔静脉壁整块切除,下腔静脉用牛心包重建。

结论

尽管肿瘤直接侵犯或肿瘤血栓延伸至下腔静脉(或两者皆有),仍可实现完整(R0)切除。因此,这种情况不应排除对肾上腺癌患者进行根治性切除的尝试。

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引用本文的文献

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Tumor thrombus: incidence, imaging, prognosis and treatment.肿瘤血栓:发病率、影像学、预后及治疗
Cardiovasc Diagn Ther. 2017 Dec;7(Suppl 3):S165-S177. doi: 10.21037/cdt.2017.09.16.
2
Long-term recurrence-free survival of adrenocortical cancer extending into the inferior vena cava and right atrium: Case report and literature review.肾上腺皮质癌侵犯下腔静脉和右心房的长期无复发生存:病例报告及文献综述
Medicine (Baltimore). 2017 May;96(18):e6751. doi: 10.1097/MD.0000000000006751.
3
Adrenocortical carcinoma with inferior vena cava, left renal vein and right atrium tumor thrombus extension.
肾上腺皮质癌伴下腔静脉、左肾静脉及右心房肿瘤血栓延伸。
Int J Surg Case Rep. 2015;15:137-9. doi: 10.1016/j.ijscr.2015.07.008. Epub 2015 Jul 18.