Gibson Teresa B, Ng Eliza, Ozminkowski Ronald J, Wang Shaohung, Burton Wayne N, Goetzel Ron Z, Maclean Ross
Thomson Healthcare, Research Division, Ann Arbor, Mich 48108, USA.
J Occup Environ Med. 2008 Nov;50(11):1261-72. doi: 10.1097/JOM.0b013e318181b8ca.
To estimate the direct medical and indirect (absenteeism and short-term disability) cost burden of Crohn's Disease (CD) and Ulcerative Colitis (UC).
Data were obtained from 1999 to 2005 MarketScan databases. Twelve-month expenditures for patients with CD and UC were compared to expenditures among an equal number of propensity score matched comparison group patients. Regression analysis controlled for demographics and case-mix.
Annual medical expenditures were significantly higher for commercially insured CD and UC patients compared to matched comparison group patients ($18,963 vs $5300 for CD patients, $15,020 vs $4982 for UC patients, respectively, all P < 0.001). Indirect costs were also high for employed patients with these conditions.
CD and UC are costly diseases with a significant cost burden related to health care utilization and productivity loss.
评估克罗恩病（CD）和溃疡性结肠炎（UC）的直接医疗成本以及间接（旷工和短期残疾）成本负担。
数据取自1999年至2005年的MarketScan数据库。将CD和UC患者的12个月支出与相同数量的倾向评分匹配对照组患者的支出进行比较。回归分析对人口统计学和病例组合进行了控制。
与匹配的对照组患者相比，商业保险的CD和UC患者的年度医疗支出显著更高（CD患者分别为18,963美元和5300美元，UC患者分别为15,020美元和4982美元，所有P<0.001）。患有这些疾病的在职患者的间接成本也很高。
CD和UC是高成本疾病，与医疗保健利用和生产力损失相关的成本负担显著。
