克罗恩病和溃疡性结肠炎的直接及间接成本负担
The direct and indirect cost burden of Crohn's disease and ulcerative colitis.
作者信息
Gibson Teresa B, Ng Eliza, Ozminkowski Ronald J, Wang Shaohung, Burton Wayne N, Goetzel Ron Z, Maclean Ross
机构信息
Thomson Healthcare, Research Division, Ann Arbor, Mich 48108, USA.
出版信息
J Occup Environ Med. 2008 Nov;50(11):1261-72. doi: 10.1097/JOM.0b013e318181b8ca.
OBJECTIVE
To estimate the direct medical and indirect (absenteeism and short-term disability) cost burden of Crohn's Disease (CD) and Ulcerative Colitis (UC).
METHODS
Data were obtained from 1999 to 2005 MarketScan databases. Twelve-month expenditures for patients with CD and UC were compared to expenditures among an equal number of propensity score matched comparison group patients. Regression analysis controlled for demographics and case-mix.
RESULTS
Annual medical expenditures were significantly higher for commercially insured CD and UC patients compared to matched comparison group patients ($18,963 vs $5300 for CD patients, $15,020 vs $4982 for UC patients, respectively, all P < 0.001). Indirect costs were also high for employed patients with these conditions.
CONCLUSIONS
CD and UC are costly diseases with a significant cost burden related to health care utilization and productivity loss.
目的
评估克罗恩病（CD）和溃疡性结肠炎（UC）的直接医疗成本以及间接（旷工和短期残疾）成本负担。
方法
数据取自1999年至2005年的MarketScan数据库。将CD和UC患者的12个月支出与相同数量的倾向评分匹配对照组患者的支出进行比较。回归分析对人口统计学和病例组合进行了控制。
结果
与匹配的对照组患者相比，商业保险的CD和UC患者的年度医疗支出显著更高（CD患者分别为18,963美元和5300美元，UC患者分别为15,020美元和4982美元，所有P<0.001）。患有这些疾病的在职患者的间接成本也很高。
结论
CD和UC是高成本疾病，与医疗保健利用和生产力损失相关的成本负担显著。
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