Lancioni G E, Olivetti Belardinelli M, Oliva D, Signorino M, De Tommaso M, Megna G, Singh N N, O'Reilly M F, Sigafoos J
Department of Psychology, University of Bari, Bari, Italy
Eur J Phys Rehabil Med. 2008 Dec;44(4):449-53.
Prior to the beginning of this study, the participant (an adolescent with postcoma multiple disabilities) had learned to use a forehead-skin response to access environmental stimuli. These learning data seemed to indicate a minimally conscious state (i.e., awareness of the link between response and stimuli) in spite of 1) a previous diagnosis of postcoma vegetative state; and 2) concomitant electrophysiological measurement showing no evidence of a passive P300 response and of mismatch negativity. The present study was an effort to extend the early learning investigation with two additional responses and related stimuli to broaden learning evidence and ascertain possible choice behavior. Results indicated that the participant learned the new responses and also provided evidence of choice behavior. These data were discussed in terms of the usefulness of the learning paradigm in the assessment and rehabilitation of persons with postcoma multiple disabilities and consciousness disorders.
在本研究开始之前，该参与者（一名昏迷后患有多种残疾的青少年）已学会使用前额皮肤反应来接触环境刺激。这些学习数据似乎表明其处于最低意识状态（即意识到反应与刺激之间的联系），尽管存在以下两点情况：1）先前被诊断为昏迷后植物状态；2）同时进行的电生理测量显示没有被动P300反应和失配负波的证据。本研究旨在通过另外两种反应及相关刺激来扩展早期学习调查，以拓宽学习证据并确定可能的选择行为。结果表明，该参与者学会了新的反应，并且还提供了选择行为的证据。从学习范式在昏迷后患有多种残疾和意识障碍者的评估与康复中的作用方面对这些数据进行了讨论。
