尿酸能否为患有高血压的孕妇的母体状况和胎儿结局提供信息？
Does uric acid provide information about maternal condition and fetal outcome in pregnant women with hypertension?
作者信息
Paula Letícia Germany, da Costa Bartira Ercília Pinheiro, Poli-de-Figueiredo Carlos Eduardo, Antonello Ivan Carlos Ferreira
机构信息
Programa de Pós-graduação em Clínica Médica e Ciências da Saúde (Nefrologia), Faculdade de Medicina/Hospital São Lucas, Pontificia Universidade Católica do Rio Grande do Sul., Porto Alegre, RS, Brazil.
出版信息
Hypertens Pregnancy. 2008;27(4):413-20. doi: 10.1080/10641950801955709.
OBJECTIVE
To evaluate associations between maternal serum uric acid (UA) levels, maternal status, and fetal outcome.
METHODS
Maternal UA, urinary protein-creatinine ratio (P/C), blood pressure (BP), gestational age at delivery, and birth weight were evaluated in hypertensive pregnant women (n = 58). These were divided into two groups: high UA (> or =357 micromol/L) or normal UA (<357 micromol/L).
RESULTS
Maternal diastolic BP and P/C ratio were higher in pregnant women with elevated UA levels. Systolic BP, gestational age and birth weight were not significantly different.
CONCLUSION
UA equal or above 357 micromol/L in pregnant hypertensive women was associated with proteinuria and diastolic BP, but not with fetal outcome.
目的
评估孕妇血清尿酸（UA）水平、孕妇状况与胎儿结局之间的关联。
方法
对58例高血压孕妇的母体尿酸、尿蛋白肌酐比值（P/C）、血压（BP）、分娩时孕周和出生体重进行评估。将这些孕妇分为两组：高尿酸组（≥357微摩尔/升）或正常尿酸组（<357微摩尔/升）。
结果
尿酸水平升高的孕妇其母体舒张压和P/C比值较高。收缩压、孕周和出生体重无显著差异。
结论
妊娠高血压妇女尿酸水平等于或高于357微摩尔/升与蛋白尿和舒张压有关，但与胎儿结局无关。
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