Leifert J A, Bossaller L, Uhl M
Department Internal Medicine, University Hospital Freiburg, Germany.
Vasa. 2008 Nov;37(4):374-8. doi: 10.1024/0301-1526.37.4.374.
Accidental intra-arterial injection of drugs is a sporadic complication in i.v. drug addicts. A 22-year-old drug-abuser injected flunitrazepam tablets dissolved in tap water into her left femoral artery and presented with clinical signs of acute ischaemia of the left leg. Severe rhabdomyolysis developed within 5 hours after the injection. Selective arterial catheter angiography showed an acute occlusion of the posterior tibial artery. Combination therapy with i.a. urokinase, i.a. prostaglandines and i.v. anticoagulation resulted in re-opening of the obstructed distal artery and complete cessation of symptoms.
药物意外动脉内注射是静脉注射吸毒者中偶发的一种并发症。一名22岁的药物滥用者将溶解于自来水中的氟硝西泮片剂注入其左股动脉，随后出现左腿急性缺血的临床症状。注射后5小时内发生了严重的横纹肌溶解。选择性动脉导管血管造影显示胫后动脉急性闭塞。动脉内使用尿激酶、动脉内使用前列腺素以及静脉抗凝的联合治疗使阻塞的远端动脉重新开通，症状完全消失。
