Aspartate carbamoyltransferase inhibition and uridylate trapping result in a synergistic depression of uridine triphosphate in hepatoma cells.
作者信息
Keppler D D
出版信息
FEBS Lett. 1977 Feb 1;73(2):263-6. doi: 10.1016/0014-5793(77)80995-2.
PMID:190038
Abstract
摘要
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Aspartate carbamoyltransferase inhibition and uridylate trapping result in a synergistic depression of uridine triphosphate in hepatoma cells.天冬氨酸氨甲酰基转移酶抑制和尿苷酸捕获导致肝癌细胞中三磷酸尿苷协同性降低。
FEBS Lett. 1977 Feb 1;73(2):263-6. doi: 10.1016/0014-5793(77)80995-2.
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引用本文的文献
1
Uridylate trapping, induction of UTP deficiency, and stimulation of pyrimidine synthesis de novo by D-galactosone.尿苷酸捕获、UTP缺乏的诱导以及D-半乳糖酮对嘧啶从头合成的刺激。
Biochem J. 1982 Jul 15;206(1):139-46. doi: 10.1042/bj2060139.
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