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[人体前臂肌肉振动反应期间的皮质脊髓兴奋性]

[Corticospinal excitabillity during vibratory reaction of forearm muscles in man].

作者信息

Talis V L, Solopova I A, Kazennikova O V

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 2008 Sep-Oct;58(5):552-61.

PMID:19004315
Abstract

We investigated the effects of forearm flexor/extensor muscles vibration on corticospinal excitability by means of transcranial magnetic stimulation (TMS) in healthy subjects. Motor evoked potentials (MEPs) and ongoing baseline activity of forearm flexor and extensor muscles were analyzed during muscle activity increase produced by vibration of these muscles (Tonic Vibratory Reflex) and by antagonist muscle vibration in isometrical condition (Antagonist Vibratory Response) and during voluntary contraction. The results showed that the normalized MEPs of forearm flexor increased by 66% during TVR, by 75% during AVR, and by 18% during voluntary contraction of this muscle as compared to threshold value. However, the increase in MEP response produced by vibratory reactions in wrist muscles did not significantly differ from that produced by the voluntary contraction of these muscles unlike the MEP response change during vibratory and voluntary activation of the forearm muscles in our previous article. Different involvement of the motor cortex in the control of vibratory reactions of the distal and proximal muscles is discussed.

摘要

我们通过经颅磁刺激(TMS)研究了前臂屈肌/伸肌振动对健康受试者皮质脊髓兴奋性的影响。在这些肌肉振动(紧张性振动反射)、等长条件下拮抗肌振动(拮抗肌振动反应)以及自愿收缩过程中肌肉活动增加时,分析了运动诱发电位(MEP)以及前臂屈肌和伸肌的持续基线活动。结果显示,与阈值相比,前臂屈肌的标准化MEP在紧张性振动反射期间增加了66%,在拮抗肌振动反应期间增加了75%,在该肌肉自愿收缩期间增加了18%。然而,与我们之前文章中前臂肌肉振动和自愿激活期间MEP反应的变化不同,腕部肌肉振动反应产生的MEP反应增加与这些肌肉自愿收缩产生的MEP反应增加没有显著差异。本文讨论了运动皮层在控制远端和近端肌肉振动反应中的不同参与情况。

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