Chung S I, Park M H, Folk J E, Lewis M S
National Institute of Dental Research, National Institutes of Health, Bethesda, MD 20892.
Biochim Biophys Acta. 1991 Feb 15;1076(3):448-51. doi: 10.1016/0167-4838(91)90490-q.
Eukaryotic initiation factor 5A (eIF-5A, formerly known as eIF-4D) purified from human erythrocytes has been found to have a monomeric molecular weight between 17,500 and 18,000. In this study, using exclusion chromatography and analytical ultracentrifugation, we demonstrate that eIF-5A normally exists as a dimer in solution and appears to be capable of undergoing reversible association to form higher polymers.
从人红细胞中纯化得到的真核生物起始因子5A（eIF - 5A，以前称为eIF - 4D），其单体分子量在17,500至18,000之间。在本研究中，我们使用排阻色谱法和分析超速离心法证明，eIF - 5A在溶液中通常以二聚体形式存在，并且似乎能够进行可逆缔合以形成更高聚物。
