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索拉非尼成功治疗一例慢性肾衰竭转移性肾细胞癌

Successful sorafenib treatment for metastatic renal cell carcinoma in a case with chronic renal failure.

作者信息

Ruppin Sebastian, Protzel Chris, Klebingat Klaus-Jürgen, Hakenberg Oliver W

机构信息

Department of Urology, Ernst Moritz Arndt University of Greifswald, Greifswald, Germany.

出版信息

Eur Urol. 2009 Apr;55(4):986-8; quiz 988. doi: 10.1016/j.eururo.2008.10.027. Epub 2008 Oct 23.

DOI:10.1016/j.eururo.2008.10.027
PMID:19004541
Abstract

Treatment options for patients with end-stage renal disease (ESRD) and metastatic renal cell carcinoma (mRCC) are limited. We report the case of a 69-yr-old male who was treated with sorafenib after failure of immunotherapy. The treatment has resulted in remission with stable disease for 13 mo so far. Sorafenib seems to be a safe treatment option for patients with ESRD and mRCC, but further studies are required.

摘要

终末期肾病(ESRD)和转移性肾细胞癌(mRCC)患者的治疗选择有限。我们报告了一例69岁男性患者,其免疫治疗失败后接受了索拉非尼治疗。该治疗目前已使病情缓解并稳定了13个月。索拉非尼似乎是ESRD和mRCC患者的一种安全治疗选择,但仍需进一步研究。

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Successful sorafenib treatment for metastatic renal cell carcinoma in a case with chronic renal failure.索拉非尼成功治疗一例慢性肾衰竭转移性肾细胞癌
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Curr Drug Metab. 2019;20(5):361-376. doi: 10.2174/1389200220666190402143125.
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Efficacy and safety of sorafenib for treatment of Japanese metastatic renal cell carcinoma patients undergoing hemodialysis.索拉非尼治疗接受血液透析的日本转移性肾细胞癌患者的疗效和安全性。
Int J Clin Oncol. 2016 Feb;21(1):126-32. doi: 10.1007/s10147-015-0871-y. Epub 2015 Jul 11.
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Comprehensive overview of the efficacy and safety of sorafenib in advanced or metastatic renal cell carcinoma after a first tyrosine kinase inhibitor.
索拉非尼在首个酪氨酸激酶抑制剂治疗后晚期或转移性肾细胞癌中的疗效和安全性的综合概述。
Clin Transl Oncol. 2013 Jun;15(6):425-33. doi: 10.1007/s12094-012-0985-x. Epub 2013 Feb 12.
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Experience with sorafenib in the treatment of advanced renal cell carcinoma.索拉非尼治疗晚期肾细胞癌的经验。
Ther Adv Urol. 2012 Dec;4(6):303-13. doi: 10.1177/1756287212457216.