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Both telomeric and non-telomeric DNA damage are determinants of mammalian cellular senescence.
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Death receptor-induced activation of the Chk2- and histone H2AX-associated DNA damage response pathways.
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Gamma-H2AX in recognition and signaling of DNA double-strand breaks in the context of chromatin.
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Detection of histone H2AX phosphorylation on Ser-139 as an indicator of DNA damage (DNA double-strand breaks).
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