Fishman Gerald A
Department of Ophthalmology and Visual Science, Illinois Eye and Ear Infirmary, University of Illinois at Chicago, Illinois 60612-7243, USA.
Ophthalmic Genet. 2008 Dec;29(4):162-5. doi: 10.1080/13816810802251446.
John Dalton was born in the 18th century and was recognized mainly for his work on the chemical atomic theory and "Dalton's Law" for the partial pressure of gases. However, during his lifetime he was already recognized for his theories on "colorblindness," with which he was afflicted. He was perhaps the first to report personal observations from experimentation on his color vision deficiency. His theory regarding its pathogenesis was posthumously proven to be incorrect after observations performed on his enucleated eyes. Further generations later, DNA analyses by PCR conclusively recorded the specific color deficiency (deuteranopia) with which Dalton was affected.
约翰·道尔顿出生于18世纪,主要因他在化学原子理论以及气体分压的“道尔顿定律”方面的工作而被人们所认可。然而,在他的一生中,他就因其所患的“色盲症”理论而受到关注。他可能是第一个报告对自己色觉缺陷进行实验的个人观察结果的人。在对他摘除的眼球进行观察后,他关于色盲症发病机制的理论在他去世后被证明是不正确的。几代人之后,通过聚合酶链反应(PCR)进行的DNA分析最终确定了道尔顿所患的具体色盲类型(绿色盲)。