婴儿利什曼原虫引起的内脏利什曼病所致急性肾衰竭经单次高剂量脂质体两性霉素B成功治愈。

Acute renal failure due to visceral leishmaniasis by Leishmania infantum successfully treated with a single high dose of liposomal amphotericin B.

作者信息

Beltrame Anna, Arzese Alessandra, Camporese Alessandro, Rorato Giada, Crapis Massimo, Tarabini-Castellani Giuseppe, Boscutti Giuliano, Pizzolitto Stefano, Calianno Giuseppina, Matteelli Alberto, Di Muccio Trentina, Gramiccia Marina, Viale Pierluigi

机构信息

Clinic of Infectious Diseases, Department of Clinical and Morphological Research, University of Udine, Udine, Italy.

出版信息

J Travel Med. 2008 Sep-Oct;15(5):358-60. doi: 10.1111/j.1708-8305.2008.00220.x.

DOI:10.1111/j.1708-8305.2008.00220.x

PMID:19006511

Abstract

We report a visceral leishmaniasis case in an immunocompetent immigrant with acute renal failure. Parasites were demonstrated in bone marrow, peripheral blood, and kidney samples. A collapsing focal segmental glomerulosclerosis was documented, which was successfully treated with a single infusion of 10 mg/kg liposomal amphotericin B.

摘要

我们报告了一例免疫功能正常的移民患内脏利什曼病并伴有急性肾衰竭的病例。在骨髓、外周血和肾脏样本中均发现了寄生虫。记录显示存在局灶节段性肾小球硬化伴塌陷，通过单次静脉输注10mg/kg脂质体两性霉素B成功治愈。